G Lazzarino , B Giardina and B Chance metabolism . Mechanism of the effect of exogenous fructose 1 , 6 - bisphosphate on myocardial energy
نویسندگان
چکیده
metabolism. Mechanism of the effect of exogenous fructose 1,6-bisphosphate on myocardial energy Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 1991 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.83.2.584 1991;83:584-593 Circulation. http://circ.ahajournals.org/content/83/2/584 the World Wide Web at: The online version of this article, along with updated information and services, is located on
منابع مشابه
Myocardial metabolism of exogenous FDP is consistent with transport by a dicarboxylate transporter.
The extent to and the mechanism by which fructose-1,6-bisphosphate (FDP) crosses cell membranes are unknown. We hypothesized that its transport is either via band 3 or a dicarboxylate transporter. The question was addressed in isolated Langendorff rat hearts perfused under normoxic conditions. Groups of hearts received the following metabolic substrates (in mM): 5 FDP; 5 FDP + either 5, 10, or ...
متن کاملKinetic Aspects of Tetrahydrobenzo[b]pyran Formation in the Presence of Fructose as a Green Catalyst: a Mechanistic Investigation
The kinetics and mechanism of the reaction between benzaldehyde 1, malononitrile 2 and dimedone 3 in a mixture of ethanol and water as solvents in the presence of fructose as a biodegradable catalyst has been studied by the spectroscopic method (UV-Vis spectrophotometry method). The influence of various parameters (temperature, solvent and concentration) was studied on the reaction by means of ...
متن کاملRole of fructose 2,6-bisphosphate in the regulation of glycolysis and gluconeogenesis in chicken liver.
Glucagon and dibutyryl cyclic AMP inhibited glucose utilization and lowered fructose 2,6-bisphosphate levels of hepatocytes prepared from fed chickens. Partially purified preparations of chicken liver 6-phosphofructo-1-kinase and fructose 1,6-bisphosphatase were activated and inhibited by fructose 2,6-bisphosphate, respectively. The sensitivities of these enzymes and the changes observed in fru...
متن کاملA new level of regulation in gluconeogenesis: metabolic state modulates the intracellular localization of aldolase B and its interaction with liver fructose-1,6-bisphosphatase.
Understanding how glucose metabolism is finely regulated at molecular and cellular levels in the liver is critical for knowing its relationship to related pathologies, such as diabetes. In order to gain insight into the regulation of glucose metabolism, we studied the liver-expressed isoforms aldolase B and fructose-1,6-bisphosphatase-1 (FBPase-1), key enzymes in gluconeogenesis, analysing thei...
متن کاملHypertrehalosaemic neuropeptides decrease levels of the glycolytic signal fructose 2,6-bisphosphate in cockroach fat body
In cockroach fat body, trehalogenesis and glycolysis compete for glucose phosphates as common substrates. During trehalogenesis, glycolysis is inhibited, although the mechanism responsible for this is not known. Incubation of the isolated fat body from the Argentine cockroach Blaptica dubia with an extract of the corpora cardiaca containing as little as 0.005 gland equivalents ml-1 of incubatio...
متن کامل